Categories Vitamin D3

Vitamin D in cancer therapy

The dental news portal zm-online and the website for medical news DocCheck recently published a statement at the same time on the latest studies concerning vitamin D in oncology (1,2). Both websites refer to a team of researchers from Cologne, who identified a relationship between vitamin D deficiency and survival rate in patients with Hodgkin’s lymphoma (3).
Despite the available scientific data and increasing evidence for the outstanding importance of vitamin D, regular vitamin D determination is not recommended in current guidelines. Furthermore, there is no recommendation for a vitamin D supplementation. This is based on the fact that the actual benefit of administering vitamin D to patients has not yet been verified. It is suggested to implement further studies to prove the positive influence of vitamin D on the survival rate of cancer patients. In case of positive results, the determination and supplementation of vitamin D and other vitamins can be included in the oncological routine (1).
Read More Vitamin D in cancer therapy

Categories Biological Dentistry

Current statement of the FDA about dental amalgam and implanted metal devices

Current statement of the FDA about dental amalgam and implanted metal devices: „Implanted metal devices, dental amalgam to go under FDA’s microscope.“

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Figure 1: U.S. Food & Drug Administration (1)

The U.S. Food and Drug Administration (FDA) wants dental amalgam and implanted metal devices (like titanium implants) to go under FDA’s microscope. On November 13-14 2019, a public meeting of the Immunology Devices Panel of the Medical Devices Advisory Committee will take place, which is expected eagerly (1).

But what is the purpose of the FDA to deal with this issue?

Such a meeting is overdue, hopefully it will provide the necessary steps and bans to protect the population from the health risks associated with the use of metals in the oral cavity. The risks are well-known and scientifically proven:

Dental amalgam

50% of dental amalgam is elemental mercury. Mercury is one of the most toxic, non-radioactive elements on our planet (2,3). According to the European mercury regulation, dental facilities should be equipped with amalgam separators to protect waste water and our environment from further pollution. After being removed, amalgam must be disposed of as highly toxic hazardous waste, which is a financial burden for the dental office. Nevertheless, in Germany the percentage of dental amalgam fillings still is around 30% (4). Each year, approximately 15 tons of mercury are required for dental amalgam fillings (3,5). 

From 1 July 2018, dental amalgam should not be used in the treatment of children under 15 years of age and in pregnant or breastfeeding women (5). In Norway, Sweden, Denmark, Russia and Japan, amalgam is already completely banned for its use. 

In 1992, Dr. Ulrich Volz wrote his doctoral thesis on the risks of amalgam (Title: “Qualitative investigations of amalgam invasion into the dental pulp”). Small amalgam fillings in wisdom teeth were used to investigate the release of amalgam in the tissue. He demonstrated that amalgam was found directly in the pulp and in the cell nuclei of the tissue after just 24 hours (6).

Many studies proved already the negative health effects of mercury. It is associated with neurodegenerative diseases such as Parkinson’s disease and multiple sclerosis (7–9). Autism (especially in children) is related to a high mercury level (10,11). An increasing number of maternal dental amalgam fillings correlates with increased fetal exposure in utero. Human placenta does not represent a real barrier to the transport of mercury (12–14). Due to its neuro- and immunotoxic potential, mercury is considered by the WHO as one of the top ten chemicals of major public health concern (15). The half-life of inorganic mercury in the human brain is estimated to be several years to decades (3). 

The following x-ray of a sheep demonstrates the accumulation of mercury in the entire organism only 24 hours after placing amalgam fillings. The most affected organs are the kidneys, liver and stomach:

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Figure 2: How mercury get’s out of amalgam and into your body (16)

Even after 50 years of wearing, mercury vapor can be released from amalgam fillings: 

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Figure 3: youtube video smoking teeth = poison gas (17)

Titanium implants

Besides dental amalgam as an intraoral interference field, implanted metal devices like titanium dental implants may have negative health effects on the entire organism. In September 2019, the traditional dental society “New Group” dedicated an entire congress to ceramic implantology. Prof. Terheyden, president of the German Association of Oral Implantology (DGI) from 2010-2013, stated that titanium is a highly reactive material and emphasized growing evidence for the biocorrosion of this metal. At the ESCI Congress (European Society of Ceramic Implantology) in Zurich this year, the multiple negative effects of titanium implants on the organism were discussed. Due to corrosion of the titanium surface, titanium particles will be released which infiltrate the surrounding tissue. The particles may be associated with the development of periimplantitis and implant loss (18–21). 

The following figure shows the x-ray and the intraoral picture of periimplantitis. Bone loss and exposed implant threads are visible: 

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Figure 4: Hessam N, Jorgensen M. Dental Implant Maintenance (22)

Factors that contribute to corrosion are of mechanical, chemical and electrolytic origin (23). Particle release occurs due to mechanical friction during insertion of the implant and/or micromovements of the implant while chewing (19,24). Macrophages react to contact with titanium oxide particles causing an immune response by releasing pro-inflammatory cytokines like tumor necrosis factor-α (TNF-α, an inflammatory messenger) and interleukin-1β (IL-1β); osteoclasts are activated and bone and tissue resorption can occur (25–28): 

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Figure 5: left: Hallab NJ, Jacobs JJ: Biologic effects of implant debris (28) and right: Olmedo et al: Oral mucosa tissue response to titanium cover screws: lymphocytes associated with a metal particle (arrow) (29)

The released particles are a constant stimulus for the body’s immune system, producing a chronic immunological reaction. Besides local effects, the released pro-inflammatory cytokines have systemic impacts on many tissues such as muscles, endothelium and the nervous system (see figure 6) (25,30). Thus, systemic diseases such as rheumatoid arthritis, multiple sclerosis, tumors, breast carcinomas and cardiovascular diseases can be initiated by titanium implants due to an overexpression of TNF-α (31).

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Figure 6: Dr. Elisabeth Jakobi-Gresser: Pathogenesis of periimplantitis (32) 

Furthermore, titanium oxide nanoparticles have cytotoxic and genotoxic potential and cause oxidative stress (33). Studies have been published that associate neoplasms such as osteosarcoma, plasmocytoma or breast metastasis  with titanium dental implants (34–36). Metals such as titanium can cause hypersensitivity and allergic reactions (37–39). Harloff et al. found traceable amounts of palladium, nickel and chromium in implant material samples. These elements also can be associated with allergic reactions. Nickel, which is one of the main allergens and causes sensitization in about 12% of the population is present in all titanium dental implants. Due to its low content, manufacturers do not have to label it, but even these small amounts may be sufficient to trigger allergic reactions (40):

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Figure 7: Harloff et al.: Titanium allergy or not? “Impurity“ of titanium implant materials (40)

In summary, amalgam and other metals such as titanium should not be incorporated into the human body. A safe protocol to remove them is necessary. In particular dental amalgam fillings should be removed under high protection measures to avoid further exposure to mercury vapors. The biocompatible zirconium dioxide (used in the Swiss Biohealth Clinic) instead of titanium for dental implants offers a biological, non-reactive alternative and protects patients’ health. Another important aspect is to avoid food or cosmetics which contain metals such as titanium dioxide or heavy metals (see titanium dioxide particles in our food at https://www.swiss-biohealth.com/blog/). 

The meeting of the FDA’ s Committee on 13-14 November 2019 will hopefully consider these serious problems and risks and draw the necessary conclusions. Under following link, it will be possible to attend the meeting live and online: https://www.fda.gov/medical-devices/dental-devices/dental-amalgam 

 

References

1. U.S. Food & Drug Administration. Dental Amalgam [Internet]. 2019 [cited 2019 Nov 4]. Available from: https://www.fda.gov/medical-devices/dental-devices/dental-amalgam

2. U.S. Food & Drug Administration. About Dental Amalgam Fillings [Internet]. 2017 [cited 2019 Nov 4]. Available from: https://www.fda.gov/medical-devices/dental-amalgam/about-dental-amalgam-fillings#top

3. Mutter J. Gesund statt chronisch krank!: Der ganzheitliche Weg: Vorbeugung und Heilung sind möglich. 3rd ed. Weil der Stadt: Fit fürs Leben Verlag; 2014. 456 Seiten. (Gesundheit).

4. KZBV. Bundesrat verabschiedet Minamata-Übereinkommen [Internet]. Pressemitteilung vom 2017 [cited 2019 Nov 4]. Available from: https://www.kzbv.de/pressemitteilung-vom-2-6-2017.1146.de.html

5. Bundeszahnärztekammer. EU-Quecksilberverordnung: Verordnung (EU) 2017/852 [Internet]. 2018 [cited 2019 Nov 4]. Available from: https://www.bzaek.de/fileadmin/PDFs/b/Position_Amalgam.pdf

6. Volz U. Qualitative Untersuchungen zur Amalgaminvasion in die Zahnpulpa.: Inaugural-Dissertation zur Erlangung der Doktorwürde. Ulm;1992. 

7. Bjorklund G, Stejskal V, Urbina MA, Dadar M, Chirumbolo S, Mutter J. Metals and Parkinson’s Disease: Mechanisms and Biochemical Processes. Curr Med Chem. 2018;25(19):2198–214. doi:10.2174/0929867325666171129124616

8. Bjørklund G, Hilt B, Dadar M, Lindh U, Aaseth J. Neurotoxic effects of mercury exposure in dental personnel. Basic Clin Pharmacol Toxicol. 2019;124(5):568–74. doi:10.1111/bcpt.13199

9. Cariccio VL, Samà A, Bramanti P, Mazzon E. Mercury Involvement in Neuronal Damage and in Neurodegenerative Diseases. Biol Trace Elem Res. 2019;187(2):341–56. doi:10.1007/s12011-018-1380-4

10. Jafari T, Rostampour N, Fallah AA, Hesami A. The association between mercury levels and autism spectrum disorders: A systematic review and meta-analysis. J Trace Elem Med Biol. 2017;44289–97. doi:10.1016/j.jtemb.2017.09.002

11. Kern JK, Geier DA, Sykes LK, Haley BE, Geier MR. The relationship between mercury and autism: A comprehensive review and discussion. J Trace Elem Med Biol. 2016;378–24. doi:10.1016/j.jtemb.2016.06.002

12. Ask K, Akesson A, Berglund M, Vahter M. Inorganic mercury and methylmercury in placentas of Swedish women. Environ Health Perspect. 2002;110(5):523–6. doi:10.1289/ehp.02110523

13. Palkovicova L, Ursinyova M, Masanova V, Yu Z, Hertz-Picciotto I. Maternal amalgam dental fillings as the source of mercury exposure in developing fetus and newborn. J Expo Sci Environ Epidemiol. 2008;18(3):326–31. doi:10.1038/sj.jes.7500606

14. Vahter M, Akesson A, Lind B, Björs U, Schütz A, Berglund M. Longitudinal study of methylmercury and inorganic mercury in blood and urine of pregnant and lactating women, as well as in umbilical cord blood. Environ Res. 2000;84(2):186–94. doi:10.1006/enrs.2000.4098

15. World Health Organization. Mercury and health [Internet]. 2017 [cited 2019 Nov 4]. Available from: https://www.who.int/news-room/fact-sheets/detail/mercury-and-health

16. Mercury in my mouth. Mercury 102 – How mercury get’s out of amalgam and into your body [Internet]. 2011 [cited 2019 Nov 4]. Available from: https://mercuryinmymouth.wordpress.com/2011/03/01/mercury-102-how-mercury-gets-out-of-amalgam-and-into-your-body/

17. IAOMT.org. SMOKING TEETH = POISON GAS [Internet]: siehe youtube Video [cited 2019 Nov 4]. Available from: https://www.youtube.com/watch?v=8UUjvunT4cg

18. Barão VAR, Yoon CJ, Mathew MT, Yuan JC-C, Wu CD, Sukotjo C. Attachment of Porphyromonas gingivalis to corroded commercially pure titanium and titanium-aluminum-vanadium alloy. J Periodontol. 2014;85(9):1275–82. doi:10.1902/jop.2014.130595

19. Delgado-Ruiz R, Romanos G. Potential Causes of Titanium Particle and Ion Release in Implant Dentistry: A Systematic Review. Int J Mol Sci. 2018;19(11). doi:10.3390/ijms19113585

20. Safioti LM, Kotsakis GA, Pozhitkov AE, Chung WO, Daubert DM. Increased Levels of Dissolved Titanium Are Associated With Peri-Implantitis – A Cross-Sectional Study. J Periodontol. 2017;88(5):436–42. doi:10.1902/jop.2016.160524

21. Fretwurst T, Nelson K, Tarnow DP, Wang H-L, Giannobile WV. Is Metal Particle Release Associated with Peri-implant Bone Destruction? An Emerging Concept. J Dent Res. 2018;97(3):259–65. doi:10.1177/0022034517740560

22. Hessam Nowzari DDS, PhD and Michael Jorgensen, DDS. Dental Implant Maintenance [Internet]. 2014 [cited 2019 Nov 4]. Available from: http://www.theendoblog.com/2014/01/dental-implant-maintenance.html

23. Apaza-Bedoya K, Tarce M, Benfatti CAM, Henriques B, Mathew MT, Teughels W, Souza JCM. Synergistic interactions between corrosion and wear at titanium-based dental implant connections: A scoping review. J Periodont Res. 2017;52(6):946–54. doi:10.1111/jre.12469

24. Senna P, Antoninha Del Bel Cury A, Kates S, Meirelles L. Surface Damage on Dental Implants with Release of Loose Particles after Insertion into Bone. Clin Implant Dent Relat Res. 2015;17(4):681–92. doi:10.1111/cid.12167

25. IMD Labor Berlin. Titan-Unverträglichkeit [Internet] [cited 2019 Nov 4]. Available from: https://www.imd-berlin.de/fachinformationen/diagnostikinformationen/titan-unvertraeglichkeit.html

26. Olmedo D, Fernández MM, Guglielmotti MB, Cabrini RL. Macrophages related to dental implant failure. Implant Dent. 2003;12(1):75–80. 

27. Sterner T, Schütze N, Saxler G, Jakob F, Rader CP. Auswirkungen von klinisch relevanten Aluminium Keramik-, Zirkonium Keramik- und Titanpartikel unterschiedlicher Grösse und Konzentration auf die TNFalpha-Ausschüttung in einem humanen Makrophagensystem [Effects of clinically relevant alumina ceramic, zirconia ceramic and titanium particles of different sizes and concentrations on TNF-alpha release in a human macrophage cell line]. Biomed Tech (Berl). 2004;49(12):340–4. ger. doi:10.1515/BMT.2004.063

28. Hallab NJ, Jacobs JJ. Biologic effects of implant debris. Bull NYU Hosp Jt Dis. 2009;67(2):182–8. 

29. Olmedo DG, Paparella ML, Spielberg M, Brandizzi D, Guglielmotti MB, Cabrini RL. Oral mucosa tissue response to titanium cover screws. J Periodontol. 2012;83(8):973–80. doi:10.1902/jop.2011.110392

30. Rader CP, Sterner T, Jakob F, Schütze N, Eulert J. Cytokine response of human macrophage-like cells after contact with polyethylene and pure titanium particles. J Arthroplasty. 1999;14(7):840–8. doi:10.1016/s0883-5403(99)90035-9

31. Lechner J, Noumbissi S, Baehr V v. Titanium implants and silent inflammation in jawbone-a critical interplay of dissolved titanium particles and cytokines TNF-α and RANTES/CCL5 on overall health? EPMA J. 2018;9(3):331–43. doi:10.1007/s13167-018-0138-6

32. Jacobi-Gresser E. Pathogenese der Periimplantitis [Internet]. 2019 [cited 2019 Nov 6]. Available from: https://www.dimagazin-aktuell.de/implantologie/periimplantitis/story/pathogenese-der-periimplantitis__6705.html

33. Khan M, Naqvi AH, Ahmad M. Comparative study of the cytotoxic and genotoxic potentials of zinc oxide and titanium dioxide nanoparticles. Toxicol Rep. 2015;2765–74. doi:10.1016/j.toxrep.2015.02.004

34. McGuff HS, Heim-Hall J, Holsinger FC, Jones AA, O’Dell DS, Hafemeister AC. Maxillary osteosarcoma associated with a dental implant: report of a case and review of the literature regarding implant-related sarcomas. J Am Dent Assoc. 2008;139(8):1052–9. doi:10.14219/jada.archive.2008.0307

35. Poggio CE. Plasmacytoma of the mandible associated with a dental implant failure: a clinical report. Clin Oral Implants Res. 2007;18(4):540–3. doi:10.1111/j.1600-0501.2007.01361.x

36. Dib LL, Soares AL, Sandoval RL, Nannmark U. Breast metastasis around dental implants: a case report. Clin Implant Dent Relat Res. 2007;9(2):112–5. doi:10.1111/j.1708-8208.2007.00033.x

37. Sicilia A, Cuesta S, Coma G, Arregui I, Guisasola C, Ruiz E, Maestro A. Titanium allergy in dental implant patients: a clinical study on 1500 consecutive patients. Clin Oral Implants Res. 2008;19(8):823–35. doi:10.1111/j.1600-0501.2008.01544.x

38. Thomas P, Braathen LR, Dörig M, Auböck J, Nestle F, Werfel T, Willert HG. Increased metal allergy in patients with failed metal-on-metal hip arthroplasty and peri-implant T-lymphocytic inflammation. Allergy. 2009;64(8):1157–65. doi:10.1111/j.1398-9995.2009.01966.x

39. Vijayaraghavan V, Sabane AV, Tejas K. Hypersensitivity to titanium: a less explored area of research. J Indian Prosthodont Soc. 2012;12(4):201–7. doi:10.1007/s13191-012-0139-4

40. Harloff T, Hönle W, Holzwarth U, Bader R, Thomas P, Schuh A. Titanium allergy or not? “Impurity” of titanium implant materials. Health. 2010;02(04):306–10. doi:10.4236/health.2010.24045

k2 mk7
Categories Vitamin D3

Vitamin K2 / Mk7 – another superhero vitamin?

On August 4th, I was invited to give a four-hour lecture on biological dentistry and zirconia implants to more than 300 biological physicians and dentists as part of the state-accredited Post Graduate Education program of Dr. Lair Ribeiro in São Paulo. Dr. Ribeiro is the icon for biological medicine in South America. Professional cardiologist, author of 140 scientific publications and 38 books, including 15 bestsellers in 40 different countries. Read More Vitamin K2 / Mk7 – another superhero vitamin?

titanium dioxide
Categories Uncategorized

Titanium dioxide particles in our diet

Titanium dioxide particles in our diet – effects on the tolerability of titanium implants?

A study by the University of Sydney on the effects of titanium oxide particles (TiO2) in the gut, published in May 2019, rekindled the international debate in the institutes and media about the use of titanium dioxide in our foods, marked by E171. (1-3)

Titanium dioxide: E171 and Cl77891 – where we encounter the nanoparticles

The whitening agent titanium dioxide has meanwhile become indispensable in our everyday lives, with consumption having increased sharply in the last century. The additive E171 is found in medicines, plastics, chewing gum, paints, clothing and also in our food, such as mozzarella, instant soups and sweets. Read More Titanium dioxide particles in our diet

schlaf
Categories EMF

Deep Sleep = Anti Aging?

My personal and professional involvement in biological medicine and dentistry for over 30 years has shown me that there are a few key factors that have an oversized effect on our health and performance according to the Pareto principle (80/20 principle). Biological dentistry shows an outstanding special position here, as the dead teeth and toxic materials in the oral cavity are responsible for about 60 to 80% of all chronic diseases according to estimates of opinion leaders and our own observations. Read More Deep Sleep = Anti Aging?

Mobilfunk Implantate
Categories EMF

Mobile communication and healing of implants

Mobile radio reduces the healing of dental implants by disturbing the bone metabolism and increasing the tendency for inflammation. After Brussels, Geneva now also rejects the introduction of 5G technology.

cell phone radiation

This exciting study was found by Max Riemann, an SDS user and member of our SWISS BIOHEALTH EDUCATION training center and communication platform. The Pubmed study shows that titanium implants exposed to mobile phones in the healing phase are less healthy, have less bone contact and are more susceptible to inflammation:  Read More Mobile communication and healing of implants

swiss biohealth store
Categories SWISS BIOHEALTH CONCEPT

Swiss Biohealth Store & Café and Apartment

Since the 1stof April, our Swiss Biohealth patients and Swiss Biohealth Education students can enjoy further services: The Swiss Biohealth Store & Cafè (Juicery inside) offers a wide selection of the tastiest and healthiest products. And in the Swiss Biohealth Apartment, the newly-operated patients can expect perfect conditions for a healthy and healing stay!

Swiss Biohealth Store & Café

The Swiss Biohealth Store & Café is located in the same building complex of the Clinic and the Education Centre. Stylistically, the Swiss Biohealth Store & Café is in no way inferior to the Swiss Biohealth Clinic and the Education Centre and creates a healthy and comfortable environment for your stay with us. The spacious lounge area invites you to linger long time for family relatives and accompanying persons. Read More Swiss Biohealth Store & Café and Apartment

vollnarkose
Categories Biological Dentistry

Calming, sedation or general anesthesia?

What is the best option for my upcoming surgery?

In this blog post, I would like to inform you about the various options and our biological doctor and anesthesiologist Michael Jürges, who has been working since last fall under the direction of Klinghardt and dr. Volz and complements the medical department of the SWISS BIOHEALTH CLINIC.

As you hear from us over and over, already “prayer-like” , the parasympathetic mode as an opponent to the stress mode is an indispensable prerequisite for healing and regeneration! That’s why we at the SWISS BIOHEALTH CLINIC do our outmost to promote and establish this healing state as often, in the most possible sustainable and deep way around your treatment! Through the “All-you-can-treat” My BIOHEALTH Week package, the cost guarantee of your treatment plan, the extremely well trained and emotionally intelligent team members, the EMF shielding of the clinic, the personal and friendly interaction with each other and last but Not least a high quality minimally intensive atraumatic operation by experienced specialists. Read More Calming, sedation or general anesthesia?

dr ulrich volz
Categories All in one, Biological Dentistry, MY BIOHEALTH WEEK

My own ALL IN ONE surgery – the weeks after

In this blog post I will report on the further regeneration after my own operation, which I have continued in the completely radio-free nature of Brazil. This shows how important it is – especially after surgery – to avoid EMF as much as possible. You can also achieve this at home, and I will give you all the information about it! In addition, I will show the central importance of the movement in nature and explain the benefit especially for chronically ill people. If you have not read the first part, feel free to do so here. Read More My own ALL IN ONE surgery – the weeks after

root cause
Categories Biological Dentistry, Root Cause

Root Cause – the root of all evil?

The film “Root Cause” reports on the dangers of root-treated teeth and ischemic osteonecrosis during a ten-year personal search for the cause of the chronic fatigue, the filmmaker and producer and actor Ben Purser suffers from. Rarely before has this topic generated so much audience attention as through this movie and let the waves blow up that much on both sides, the supporters of the theory as well as the opponents.
You can currently find the movie on Amazon Prime, iTunes and Vimeo.

Basically, we think it’s good that the topic Root Cause, which affects hundreds of millions of people around the world (in the US alone, around 25 million new root-canal treatments are being treated each year) is becoming a public focus and hopefully will lead to Dentists, immunologists, oncologists, cardiologists, orthopedists and internists coming together and dealing more intensively with this issue in the interest of the health of patients or humanity according to the official rules of medicine and science!

Read More Root Cause – the root of all evil?